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Index > Protein center > MBP(Gene name) > Bovine
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  • MBP (Gene name),
  • Myelin basic protein (Protein name ),  MBP_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MBP;
    Protein name:
    Myelin basic protein(MBP);
    Alternative:
    Myelin A1 protein;20 kDa microtubule-stabilizing protein;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer; self-associates in the presence of lysolipid.
    Function:
    Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane.
    Subcellular Location:
    Myelin membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic side of myelin.
    Protein Attributes:
    Sequence length:
    169
    Sequence:
    50:
    AAQKRPSQRS | KYLASASTMD | HARHGFLPRH | RDTGILDSLG | RFFGSDRGAP | 
    100:
    KRGSGKDGHH | AARTTHYGSL | PQKAQGHRPQ | DENPVVHFFK | NIVTPRTPPP | 
    150:
    SQGKGRGLSL | SRFSWGAEGQ | KPGFGYGGRA | SDYKSAHKGL | KGHDAQGTLS | 
    169:
    KIFKLGGRDS | RSGSPMARR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine MBP
    Cat.:
    E0539p
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine MBP
    Cat.:
    E0539c
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine MBP
    Cat.:
    E0539m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine MBP
    Cat.:
    E0539h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine MBP
    Cat.:
    E0539r
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine MBP
    MSDS:
    Please sign in first.
    ELISA Kit for Bovine MBP
    Cat.:
    E0539b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MBP
    Cat.:
    U0539p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MBP
    Cat.:
    U0539m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MBP
    Cat.:
    U0539h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MBP
    Cat.:
    U0539r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MBP
    Cat.:
    U0539b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine MBP
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine MBP
    Cat.:
    U0539c
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Bovine MBP
    Polyclonal Antibody for Bovine MBP
    Polyclonal Antibody for Bovine MBP
    Cat.:
    P0539Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MBP
    Cat.:
    P0539Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MBP
    Cat.:
    P0539Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine MBP
    Polyclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Monoclonal Antibody for Bovine MBP
    Protein for Bovine MBP
    Protein for Bovine MBP
    Protein for Bovine MBP
    Protein for Bovine MBP
    Protein for Bovine MBP
    Protein for Bovine MBP
    Protein for Bovine MBP

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    References
    1. 1.
      "Basic A1 protein of the myelin membrane. The complete amino acid sequence."
      Eylar E.H. , Brostoff S.W. , Hashim G. , Caccam J. , Burnett P.
      J. Biol. Chem.246:5770-5784(1971) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE
    2. 2.
      "Specific cleavage of the A1 protein from myelin with cathepsin D."
      Brostoff S.W. , Reuter W. , Hichens M. , Eylar E.H.
      J. Biol. Chem.249:559-567(1974) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "A new MBP allele in Bos taurus is characterized by BseNI PCR-RFLP."
      Pietrowski D. , Medugorac I. , Foerster M.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-56
    4. 4.
      "Encephalitogenic fragment of myelin basic protein. Amino acid sequence of bovine, rabbit, guinea pig, monkey, and human fragments."
      Shapira R. , McKneally S.S. , Chou F.C.-H. , Kibler R.F.
      J. Biol. Chem.246:4630-4640(1971)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 43-87
    5. 5.
      "Ca(2+)-calmodulin regulated effectors of microtubule stability in bovine brain."
      Pirollet F. , Derancourt J. , Haiech J. , Job D. , Margolis R.L.
      Biochemistry31:8849-8855(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 38-58 AND 119-141
      tissue: Brain.
    6. 6.
      "Purification of a new clathrin assembly protein from bovine brain coated vesicles and its identification as myelin basic protein."
      Prasad K. , Barouch W. , Martin B.M. , Greene L.E. , Eisenberg E.
      J. Biol. Chem.270:30551-30556(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-42; 74-89 AND 114-129
    7. 7.
      "Experimental allergic encephalomyelitis: synthesis of disease-inducing site of the basic protein."
      Eylar E.H. , Caccam J. , Jackson J.J. , Westall F.C. , Robinson A.B.
      Science168:1220-1223(1970) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SYNTHESIS OF ALLERGIC ENCEPHALOMYELITIS INDUCING REGION
    8. 8.
      "Localization of methylated arginine in the A1 protein from myelin."
      Brostoff S.W. , Eylar E.H.
      Proc. Natl. Acad. Sci. U.S.A.68:765-769(1971) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT ARG-106
    9. 9.
      "Basis of microheterogeneity of myelin basic protein."
      Chou F.C.-H. , Chou C.-H.J. , Shapira R. , Kibler R.F.
      J. Biol. Chem.251:2671-2679(1976) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY
    10. 10.
      "Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase."
      Erickson A.K. , Payne D.M. , Martino P.A. , Rossomando A.J. , Shabanowitz J. , Weber M.J. , Hunt D.F. , Sturgill T.W.
      J. Biol. Chem.265:19728-19735(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 97-104;PHOSPHORYLATION AT THR-97
    11. 11.
      "Determination of the sites of posttranslational modifications in the charge isomers of bovine myelin basic protein by capillary electrophoresis-mass spectroscopy."
      Zand R. , Li M.X. , Jin X. , Lubman D.
      Biochemistry37:2441-2449(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POST-TRANSLATIONAL MODIFICATIONS
    12. 12.
      "Sedimentation analysis of the self-association of bovine myelin basic protein."
      Smith R.
      Biochemistry19:1826-1831(1980) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DIMERIZATION
    13. 13.
      "Myelin basic protein undergoes a broader range of modifications in mammals than in lower vertebrates."
      Zhang C. , Walker A.K. , Zand R. , Moscarello M.A. , Yan J.M. , Andrews P.C.
      J. Proteome Res.11:4791-4802(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT ALA-1 AND LYS-121;METHYLATION AT ARG-106;DEAMIDATION AT GLN-102 AND GLN-120;CITRULLINATION AT ARG-23; ARG-47; ARG-96 AND ARG-161;PHOSPHORYLATION AT THR-97
    14. 14.
      "Identification and Characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation."
      Jin Z. , Fu Z. , Yang J. , Troncosco J. , Everett A.D. , Van Eyk J.E.
      Proteomics13:2682-2691(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CITRULLINATION AT ARG-41; ARG-63; ARG-96; ARG-106; ARG-112; ARG-129; ARG-158; ARG-161; ARG-168 AND ARG-169;METHYLATION AT ARG-106
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